Naturally It's Clean Carpet Cleaner Review: Finally, an Enzyme Cleaner That Actually Works

Yes, Naturally It's Clean actually works. In my testing, it eliminated a 3-week-old accident that survived two other cleaners within 24 hours. The plant-based formula is genuinely pet-safe, and there's no overpowering fragrance to mask the problem—just real results.
Skip to our picksYour carpet still smells. You've tried the baking soda trick, the vinegar spray, maybe even that expensive "miracle cleaner" from the pet store. Here's the thing: regular cleaners can't break down uric acid crystals—they just push them deeper into your carpet fibers.
I've tested over a dozen enzyme cleaners in the past three years. Most disappoint. But when I tried Naturally It's Clean on a particularly stubborn accident from my senior rescue dog? Gone in 24 hours. No lingering smell. No coming back when humid.
Let me walk you through exactly what happened—and whether this cleaner deserves a spot under your sink.
What Is Naturally It's Clean?
Naturally It's Clean is a plant-based enzyme cleaner designed for carpets, upholstery, and drapes. Unlike most enzyme cleaners that use synthetic formulas, this one relies on naturally-derived enzymes to break down organic matter.
Here's what sets it apart:
- Plant-based enzyme formula—no harsh chemicals
- Fragrance-free (a huge plus if you hate perfumy cleaners)
- Safe for use around pets and children
- Works on carpets, upholstery, drapes, and even mattresses
- Cruelty-free and never tested on animals
The bottle doesn't scream "pet cleaner" with cartoon dogs on it. It looks like something you'd actually want visible in your home. Small thing, but I appreciate it.

Naturally It's Clean Carpet Upholstery Cleaner
Check price on AmazonMy Testing Experience: The 3-Week-Old Accident
Let me set the scene. My 12-year-old rescue dog, Benny, has occasional accidents. Usually I catch them fast. But this one happened in a corner of the guest room I don't check often.
By the time I found it, the stain was three weeks old. I'd already tried two other cleaners on it—one drugstore brand and one "professional" cleaner. Both failed.
Here's exactly what I did with Naturally It's Clean:
- Blotted the area (even though it was dry, there was still residue)
- Sprayed liberally—I didn't skimp
- Let it sit for 30 minutes without touching it
- Blotted again with a clean white cloth
- Let it air dry completely overnight
The next morning? I got on my hands and knees and sniffed that carpet like a weirdo. Nothing. No urine smell. No chemical smell. Just... carpet.
Real talk: I went back and checked that spot every day for a week. On a humid day. After running the humidifier. The smell never came back.
Who Should Buy This?
This cleaner is ideal for:
- Pet owners dealing with recurring accidents (senior dogs, puppies in training)
- Anyone sensitive to fragrances—this is truly unscented
- Households with multiple surfaces to clean (carpet, furniture, etc.)
- People who've tried other cleaners without success

🏆Also Worth Checking: Rocco & Roxie Professional Strength Enzyme Cleaner
Professional-strength enzyme cleaner trusted by shelters and veterinarians.
It's probably overkill if you just need something for occasional spills. But for actual pet messes? This is what I reach for now.
The Honest Pros and Cons
What I Love
- Actually eliminates odors—doesn't just mask them
- No overpowering fragrance
- Safe around my pets (I watched Benny walk on the treated area with zero concern)
- Works on old, set-in stains
- The spray bottle actually works well (sounds minor, but bad spray bottles are annoying)
What Could Be Better
- Takes time to work—you need patience (not a quick fix)
- Price is higher than drugstore options
- Need to let it dry completely for best results
The price point is the main consideration. It costs more than the generic stuff at Target. But I've wasted money on three cheaper cleaners that didn't work—this one actually does the job.
Pro Tips for Best Results
After testing this for a few months, here's what I've learned:
- Don't be stingy with the spray—saturate the area
- Let it sit longer than you think (30 min minimum, overnight for tough stains)
- Blot, never rub—rubbing pushes the mess deeper
- For old stains, you might need 2-3 applications
- Keep pets away until it dries completely
Pro tip: Use a UV flashlight to find hidden accidents. You'd be surprised what you miss.
How It Compares to Alternatives
I've tried the big names. Here's how they stack up:
- Rocco & Roxie: Great cleaner, but has a slight fragrance. Naturally It's Clean wins if you're scent-sensitive.
- Nature's Miracle: Hit or miss in my experience. Works sometimes, fails others.
- Biokleen Bac-Out: Good budget option, but needed multiple applications where Naturally It's Clean worked in one.
For tough, set-in accidents? Naturally It's Clean has become my go-to.
The Bottom Line
If you're dealing with pet accidents and nothing seems to work, Naturally It's Clean is worth trying. It's not the cheapest option, but it actually does what it claims.
My verdict: This is now my primary pet stain cleaner. The 3-week-old accident test sold me. When something works on a stain that old, you pay attention.
Is it perfect? No. You need patience. You need to follow the directions. But if you're tired of cleaners that just mask the problem, this one actually solves it.

🏆✅ Our Recommendation: Naturally It's Clean Carpet Upholstery Cleaner
Plant-based enzyme cleaner for carpets, upholstery, and drapes—safe for use around pets.
Last updated: January 10, 2026





